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Glucocorticoid receptor ChIP-sequencing of primary human abdominal subcutaneous fat reveals modulation of inflammatory pathways

OBJECTIVE: To identify glucocorticoid receptor (GR)-associated chromatin sequences and target genes in primary human abdominal subcutaneous fat. METHODS: GR chromatin immunoprecipitation (ChIP)-sequencing methodology in subcutaneous human adipocytes treated ex-vivo with dexamethasone (dex) was optim...

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Foilsithe in:Obesity (Silver Spring)
Main Authors: Singh, Puneet, Brock, Clifton O., Volden, Paul A., Hernandez, Kyle, Skor, Maxwell, Kocherginsky, Masha, Park, Julie E., Brady, Matthew J., Conzen, Suzanne D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818951/
https://ncbi.nlm.nih.gov/pubmed/26408078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21251
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