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Ethanolic extract of Descurainia sophia seeds sensitizes A549 human lung cancer cells to TRAIL cytotoxicity by upregulating death receptors

BACKGROUND: Our previous genome-wide gene expression analysis revealed that tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptors 4 (DR4) and 5 (DR5) are markedly upregulated by the ethanolic extract of D. sohia seeds (EEDS) in A549 TRAIL-refractory cancer cells. In the pre...

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Publicado en:BMC Complement Altern Med
Main Authors: Park, Jong-Shik, Lim, Chae Jun, Bang, Ok-Sun, Kim, No Soo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818868/
https://ncbi.nlm.nih.gov/pubmed/27039295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-016-1094-0
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