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Propofol, but not etomidate, increases corticosterone levels and induces long-term alteration in hippocampal synaptic activity in neonatal rats

Animal studies provide strong evidence that general anesthetics (GAs), administered during the early postnatal period, induce long-term cognitive and neurological abnormalities. Because the brain growth spurt in rodents is delayed compared to that in humans, a fundamental question is whether the pos...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Xu, Changqing, Seubert, Christoph N., Gravenstein, Nikolaus, Martynyuk, Anatoly E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818705/
https://ncbi.nlm.nih.gov/pubmed/26923669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2016.02.045
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