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Arresting the Inflammatory Drive of Chronic Lymphocytic Leukemia with Ibrutinib

The clinical success of agents targeting the B cell receptor (BCR) signaling pathway in chronic lymphocytic leukemia (CLL) may also derive from disrupting the CLL microenvironment. Investigation of the immunomodulatory effects of these agents illuminates the unique immunobiology of CLL and highlight...

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Pubblicato in:Clin Cancer Res
Autori principali: Bachireddy, Pavan, Wu, Catherine J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818665/
https://ncbi.nlm.nih.gov/pubmed/26847060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-3106
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