Brinp1(−/−) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density

BACKGROUND: BMP/RA-inducible neural-specific protein 1 (Brinp1) is highly conserved in vertebrates, and continuously expressed in the neocortex, hippocampus, olfactory bulb and cerebellum from mid-embryonic development through to adulthood. METHODS: Brinp1 knock-out (Brinp1(−/−)) mice were generated...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Autism
Egile Nagusiak: Berkowicz, Susan R., Featherby, Travis J., Qu, Zhengdong, Giousoh, Aminah, Borg, Natalie A., Heng, Julian I., Whisstock, James C., Bird, Phillip I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818446/
https://ncbi.nlm.nih.gov/pubmed/27042284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-016-0079-7
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