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Long-Term Outcome of Administration of c-kit(POS) Cardiac Progenitor Cells After Acute Myocardial Infarction: Transplanted Cells Do Not Become Cardiomyocytes, Structural and Functional Improvement and Proliferation of Endogenous Cells Persist for at Least One Year

RATIONALE: Cardiac progenitor cells (CPCs) improve left ventricular (LV) remodeling and function after acute or chronic myocardial infarction (MI). However, the long-term (>5 weeks) effects, potential tumorigenicity, and fate of transplanted CPCs are unknown. OBJECTIVE: To assess the outcome of C...

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Bibliografske podrobnosti
izdano v:Circ Res
Main Authors: Tang, Xian-Liang, Li, Qianhong, Rokosh, Gregg, Sanganalmath, Santosh K., Chen, Ning, Ou, Qinghui, Stowers, Heather, Hunt, Greg, Bolli, Roberto
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818175/
https://ncbi.nlm.nih.gov/pubmed/26838790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.307647
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