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Inhibition of p300 histone acetyltransferase activity in palate mesenchyme cells attenuates Wnt signaling via aberrant E-cadherin expression

p300 is a multifunctional transcriptional coactivator that interacts with numerous transcription factors and exhibits protein/histone acetyltransferase activity. Loss of p300 function in humans and in mice leads to craniofacial defects. In this study, we demonstrated that inhibition of p300 histone...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Warner, Dennis R., Smith, Scott C., Smolenkova, Irina A., Pisano, M. Michele, Greene, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818121/
https://ncbi.nlm.nih.gov/pubmed/26921506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2016.02.015
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