Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease

BACKGROUND: Accumulating evidence has shown that methionine- and choline-deficient high fat (MCD+HF) diet induces the development of nonalcoholic fatty liver disease (NAFLD), in which elevated reactive oxygen species play a crucial role. We have reported that peroxiredoxin 4 (PRDX4), a unique secret...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Nawata, Aya, Noguchi, Hirotsugu, Mazaki, Yuichi, Kurahashi, Toshihiro, Izumi, Hiroto, Wang, Ke-Yong, Guo, Xin, Uramoto, Hidetaka, Kohno, Kimitoshi, Taniguchi, Hatsumi, Tanaka, Yoshiya, Fujii, Junichi, Sasaguri, Yasuyuki, Tanimoto, Akihide, Nakayama, Toshiyuki, Yamada, Sohsuke
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818088/
https://ncbi.nlm.nih.gov/pubmed/27035833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152549
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