A Lentiviral Vector Allowing Physiologically Regulated Membrane-anchored and Secreted Antibody Expression Depending on B-cell Maturation Status

The development of lentiviral vectors (LVs) for expression of a specific antibody can be achieved through the transduction of mature B-cells. This approach would provide a versatile tool for active immunotherapy strategies for infectious diseases or cancer, as well as for protein engineering. Here,...

Full description

Saved in:
Bibliographic Details
Published in:Mol Ther
Main Authors: Fusil, Floriane, Calattini, Sara, Amirache, Fouzia, Mancip, Jimmy, Costa, Caroline, Robbins, Justin B, Douam, Florian, Lavillette, Dimitri, Law, Mansun, Defrance, Thierry, Verhoeyen, Els, Cosset, François-Loïc
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817946/
https://ncbi.nlm.nih.gov/pubmed/26281898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.148
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items