Delivery of siRNA Using CXCR4-targeted Nanoparticles Modulates Tumor Microenvironment and Achieves a Potent Antitumor Response in Liver Cancer

Antiangiogenic therapy has recently emerged as a highly promising therapeutic strategy for treating hepatocellular carcinoma (HCC). However, the only clinically approved systemic antiangiogenic agent for advanced HCC is sorafenib, which exerts considerable toxicity. Moreover, acquired resistance to...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Liu, Jia-Yu, Chiang, Tsaiyu, Liu, Chun-Hung, Chern, Guann-Gen, Lin, Ts-Ting, Gao, Dong-Yu, Chen, Yunching
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817943/
https://ncbi.nlm.nih.gov/pubmed/26278330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.147
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