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In silico prioritization based on coexpression can aid epileptic encephalopathy gene discovery

OBJECTIVE: To evaluate the performance of an in silico prioritization approach that was applied to 179 epileptic encephalopathy candidate genes in 2013 and to expand the application of this approach to the whole genome based on expression data from the Allen Human Brain Atlas. METHODS: PubMed search...

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Publicado en:Neurol Genet
Autores principales: Oliver, Karen L., Lukic, Vesna, Freytag, Saskia, Scheffer, Ingrid E., Berkovic, Samuel F., Bahlo, Melanie
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817907/
https://ncbi.nlm.nih.gov/pubmed/27066588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000051
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