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DEC1 negatively regulates AMPK activity via LKB1

Basic helix-loop-helix (bHLH) transcription factor DEC1 (bHLHE40/Stra13/Sharp2) is one of the clock genes that show a circadian rhythm in various tissues. AMP-activated protein kinase (AMPK) activity plays important roles in the metabolic process and in cell death induced by glucose depletion. Recen...

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Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Sato, Fuyuki, Muragaki, Yasuteru, Zhang, Yanping
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817498/
https://ncbi.nlm.nih.gov/pubmed/26498531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.10.077
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