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JAM: A Scalable Bayesian Framework for Joint Analysis of Marginal SNP Effects

Recently, large scale genome‐wide association study (GWAS) meta‐analyses have boosted the number of known signals for some traits into the tens and hundreds. Typically, however, variants are only analysed one‐at‐a‐time. This complicates the ability of fine‐mapping to identify a small set of SNPs for...

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Détails bibliographiques
Publié dans:Genet Epidemiol
Auteurs principaux: Newcombe, Paul J., Conti, David V., Richardson, Sylvia
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817278/
https://ncbi.nlm.nih.gov/pubmed/27027514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21953
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