From preclinical development to clinical application: Kit formulation for radiolabelling the minigastrin analogue CP04 with In-111 for a first-in-human clinical trial

INTRODUCTION: A variety of radiolabelled minigastrin analogues targeting the cholecystokinin 2 (CCK2) receptor were developed and compared in a concerted preclinical testing to select the most promising radiotracer for diagnosis and treatment of medullary thyroid carcinoma (MTC). DOTA–DGlu–DGlu–DGlu...

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Detalhes bibliográficos
Publicado no:Eur J Pharm Sci
Main Authors: Pawlak, Dariusz, Rangger, Christine, Peitl, Petra Kolenc, Garnuszek, Piotr, Maurin, Michał, Ihli, Laura, Kroselj, Marko, Maina, Theodosia, Maecke, Helmut, Erba, Paola, Kremser, Leopold, Hubalewska-Dydejczyk, Alicja, Mikołajczak, Renata, Decristoforo, Clemens
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817208/
https://ncbi.nlm.nih.gov/pubmed/26826279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2016.01.023
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