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All Hormone-Producing Cell Types of the Pituitary Intermediate and Anterior Lobes Derive From Prop1-Expressing Progenitors

Mutations in PROP1, the most common known cause of combined pituitary hormone deficiency in humans, can result in the progressive loss of all hormones of the pituitary anterior lobe. In mice, Prop1 mutations result in the failure to initiate transcription of Pou1f1 (also known as Pit1) and lack soma...

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Vydáno v:Endocrinology
Hlavní autoři: Davis, Shannon W., Keisler, Jessica L., Pérez-Millán, María I., Schade, Vanessa, Camper, Sally A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816735/
https://ncbi.nlm.nih.gov/pubmed/26812162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1862
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