The Bifunctional Entamoeba histolytica Alcohol Dehydrogenase 2 (EhADH2) Protein Is Necessary for Amebic Growth and Survival and Requires an Intact C-terminal Domain for Both Alcohol Dehydrogenase and Acetaldehyde Dehydrogenase Activity()

The intestinal protozoan pathogen Entamoeba histolytica lacks mitochondria and derives energy from the fermentation of glucose to ethanol with pyruvate, acetyl enzyme Co-A, and acetaldehyde as intermediates. A key enzyme in this pathway may be the 97-kDa bifunctional E. histolytica alcohol dehydroge...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Espinosa, Avelina, Yan, Le, Zhang, Zhi, Foster, Lynne, Clark, David, Li, Ellen, Stanley, Samuel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816598/
https://ncbi.nlm.nih.gov/pubmed/11274185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M101349200
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