Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine

The poliovirus vaccine field is moving towards novel vaccination strategies. Withdrawal of the Oral Poliovirus Vaccine and implementation of the conventional Inactivated Poliovirus Vaccine (cIPV) is imminent. Moreover, replacement of the virulent poliovirus strains currently used for cIPV with atten...

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發表在:PLoS Pathog
Main Authors: Sanders, Barbara P., de los Rios Oakes, Isabel, van Hoek, Vladimir, Bockstal, Viki, Kamphuis, Tobias, Uil, Taco G., Song, Yutong, Cooper, Gillian, Crawt, Laura E., Martín, Javier, Zahn, Roland, Lewis, John, Wimmer, Eckard, Custers, Jerome H. H. V., Schuitemaker, Hanneke, Cello, Jeronimo, Edo-Matas, Diana
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816566/
https://ncbi.nlm.nih.gov/pubmed/27032093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005483
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