Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine

The poliovirus vaccine field is moving towards novel vaccination strategies. Withdrawal of the Oral Poliovirus Vaccine and implementation of the conventional Inactivated Poliovirus Vaccine (cIPV) is imminent. Moreover, replacement of the virulent poliovirus strains currently used for cIPV with atten...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Sanders, Barbara P., de los Rios Oakes, Isabel, van Hoek, Vladimir, Bockstal, Viki, Kamphuis, Tobias, Uil, Taco G., Song, Yutong, Cooper, Gillian, Crawt, Laura E., Martín, Javier, Zahn, Roland, Lewis, John, Wimmer, Eckard, Custers, Jerome H. H. V., Schuitemaker, Hanneke, Cello, Jeronimo, Edo-Matas, Diana
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816566/
https://ncbi.nlm.nih.gov/pubmed/27032093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005483
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