Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine

The poliovirus vaccine field is moving towards novel vaccination strategies. Withdrawal of the Oral Poliovirus Vaccine and implementation of the conventional Inactivated Poliovirus Vaccine (cIPV) is imminent. Moreover, replacement of the virulent poliovirus strains currently used for cIPV with atten...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Sanders, Barbara P., de los Rios Oakes, Isabel, van Hoek, Vladimir, Bockstal, Viki, Kamphuis, Tobias, Uil, Taco G., Song, Yutong, Cooper, Gillian, Crawt, Laura E., Martín, Javier, Zahn, Roland, Lewis, John, Wimmer, Eckard, Custers, Jerome H. H. V., Schuitemaker, Hanneke, Cello, Jeronimo, Edo-Matas, Diana
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816566/
https://ncbi.nlm.nih.gov/pubmed/27032093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005483
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