Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine

The poliovirus vaccine field is moving towards novel vaccination strategies. Withdrawal of the Oral Poliovirus Vaccine and implementation of the conventional Inactivated Poliovirus Vaccine (cIPV) is imminent. Moreover, replacement of the virulent poliovirus strains currently used for cIPV with atten...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Sanders, Barbara P., de los Rios Oakes, Isabel, van Hoek, Vladimir, Bockstal, Viki, Kamphuis, Tobias, Uil, Taco G., Song, Yutong, Cooper, Gillian, Crawt, Laura E., Martín, Javier, Zahn, Roland, Lewis, John, Wimmer, Eckard, Custers, Jerome H. H. V., Schuitemaker, Hanneke, Cello, Jeronimo, Edo-Matas, Diana
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816566/
https://ncbi.nlm.nih.gov/pubmed/27032093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005483
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