Endosomal MR1 Trafficking Plays a Key Role in Presentation of Mycobacterium tuberculosis Ligands to MAIT Cells

Mucosal-Associated Invariant T (MAIT) cells, present in high frequency in airway and other mucosal tissues, have Th1 effector capacity positioning them to play a critical role in the early immune response to intracellular pathogens, including Mycobacterium tuberculosis (Mtb). MR1 is a highly conserv...

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Pubblicato in:PLoS Pathog
Autori principali: Harriff, Melanie J., Karamooz, Elham, Burr, Ansen, Grant, Wilmon F., Canfield, Elizabeth T., Sorensen, Michelle L., Moita, Luis F., Lewinsohn, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816560/
https://ncbi.nlm.nih.gov/pubmed/27031111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005524
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