Intraocular pharmacokinetics of intravitreal vascular endothelial growth factor-Trap in a rabbit model

PURPOSE: To determine intraocular pharmacokinetic properties of intravitreally injected vascular endothelial growth factor (VEGF)-Trap in a rabbit model. METHODS: VEGF-Trap was intravitreally injected in 18 rabbit eyes. Eyes were enucleated 1 h and 1, 2, 5, 14, and 30 days after injections and immed...

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Опубликовано в: :Eye (Lond)
Главные авторы: Park, S J, Oh, J, Kim, Y-K, Park, J H, Park, J Y, Hong, H K, Park, K H, Lee, J-E, Kim, H M, Chung, J Y, Woo, S J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
Предметы:
Laboratory Study
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816356/
https://ncbi.nlm.nih.gov/pubmed/25592118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/eye.2014.329
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