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An Optimized GD2-Targeting Retroviral Cassette for More Potent and Safer Cellular Therapy of Neuroblastoma and Other Cancers

Neuroblastoma is the commonest extra cranial solid cancer of childhood. Despite escalation of treatment regimens, a significant minority of patients die of their disease. Disialoganglioside (GD2) is consistently expressed at high-levels in neuroblastoma tumors, which have been targeted with some suc...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Thomas, Simon, Straathof, Karin, Himoudi, Nourredine, Anderson, John, Pule, Martin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816271/
https://ncbi.nlm.nih.gov/pubmed/27030986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152196
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