Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells

AIM: Platycodin D, the main saponin isolated from Chinese herb Platycodonis Radix, exhibits anticancer activities against various cancer cell lines. Here we evaluated its anticancer action against human hepatocellular carcinoma cells in vitro and in vivo, and elucidated the relationship between plat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Acta Pharmacol Sin
Main Authors: Li, Ting, Xu, Xiao-huang, Tang, Zheng-hai, Wang, Ya-fang, Leung, Chung-hang, Ma, Dik-lung, Chen, Xiu-ping, Wang, Yi-tao, Chen, Yi, Lu, Jin-jian
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816242/
https://ncbi.nlm.nih.gov/pubmed/26592509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.99
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