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Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells

AIM: Platycodin D, the main saponin isolated from Chinese herb Platycodonis Radix, exhibits anticancer activities against various cancer cell lines. Here we evaluated its anticancer action against human hepatocellular carcinoma cells in vitro and in vivo, and elucidated the relationship between plat...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Li, Ting, Xu, Xiao-huang, Tang, Zheng-hai, Wang, Ya-fang, Leung, Chung-hang, Ma, Dik-lung, Chen, Xiu-ping, Wang, Yi-tao, Chen, Yi, Lu, Jin-jian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816242/
https://ncbi.nlm.nih.gov/pubmed/26592509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.99
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