Sirt1 is involved in decreased bone formation in aged apolipoprotein E-deficient mice

AIM: Apolipoprotein E (ApoE) plays an important role in the transport and metabolism of lipids. Recent studies show that bone mass is increased in young apoE(−/−) mice. In this study we investigated the bone phenotype and metabolism in aged apoE(−/−) mice. METHODS: Femurs and tibias were collected f...

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Hong, Wei, Xu, Xiao-ya, Qiu, Zhao-hui, Gao, Jian-jun, Wei, Zhan-ying, Zhen, Li, Zhang, Xiao-li, Ye, Zhi-bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816239/
https://ncbi.nlm.nih.gov/pubmed/26592520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.95
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