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Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathway

AIM: We have reported novel anticancer bioactive peptides (ACBPs) that show tumor-suppressive activities in human gastric cancer, leukemia, nasopharyngeal cancer, and gallbladder cancer. In this study, we investigated the effects of ACBPs on human colorectal cancer and the underlying mechanisms. MET...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Su, Li-ya, Shi, Ying-xu, Yan, Mei-rong, Xi, Yaguang, Su, Xiu-lan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816232/
https://ncbi.nlm.nih.gov/pubmed/26592508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.80
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