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Regulation of PP2Cm expression by miRNA-204/211 and miRNA-22 in mouse and human cells

AIM: The mitochondrial targeted 2C-type serine/threonine protein phosphatase (PP2Cm) is encoded by the gene PPM1K and is highly conserved among vertebrates. PP2Cm plays a critical role in branched-chain amino acid catabolism and regulates cell survival. Its expression is dynamically regulated by the...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Pan, Bang-fen, Gao, Chen, Ren, Shu-xun, Wang, Yi-bin, Sun, Hai-peng, Zhou, Mei-yi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816230/
https://ncbi.nlm.nih.gov/pubmed/26592513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.119
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