Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodeling

The activation of cancer-associated fibroblasts (CAFs) is a key event in tumor progression, and alternative extracellular matrix (ECM) proteins derived from CAFs induce ECM remodeling and cancer cell invasion. Here we found that miR-200 s, which are generally downregulated in activated CAFs in breas...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Tang, X, Hou, Y, Yang, G, Wang, X, Tang, S, Du, Y-E, Yang, L, Yu, T, Zhang, H, Zhou, M, Wen, S, Xu, L, Liu, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815985/
https://ncbi.nlm.nih.gov/pubmed/26068592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.78
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