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The BH3-only protein BIM contributes to late-stage involution in the mouse mammary gland

After cessation of lactation, involution of the mouse mammary gland proceeds in two distinct phases, a reversible and an irreversible one, which leads to the death and removal of alveolar cells. Cell death is preceded by the loss of STAT5 activity, which abrogates cell differentiation and gain of ST...

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Détails bibliographiques
Publié dans:Cell Death Differ
Auteurs principaux: Schuler, F, Baumgartner, F, Klepsch, V, Chamson, M, Müller-Holzner, E, Watson, C J, Oh, S, Hennighausen, L, Tymoszuk, P, Doppler, W, Villunger, A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815977/
https://ncbi.nlm.nih.gov/pubmed/26045049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.61
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