Mitigation of Tumor-Associated Fibroblast-Facilitated Head and Neck Cancer Progression With Anti–Hepatocyte Growth Factor Antibody Ficlatuzumab

IMPORTANCE: Ficlatuzumab can be used to treat head and neck squamous cell carcinoma (HNSCC) by inhibiting c-Met receptor-mediated cell proliferation, migration, and invasion. OBJECTIVE: To understand the effect of ficlatuzumab on HNSCC proliferation, migration, and invasion. DESIGN, SETTING, AND PAR...

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Publié dans:JAMA Otolaryngol Head Neck Surg
Auteurs principaux: Kumar, Dhruv, Kandl, Christopher, Hamilton, Chase D’Arcy, Shnayder, Yelizaveta, Tsue, Terance Ted, Kakarala, Kiran, Ledgerwood, Levi, Sun, Xiuzhi Susan, Huang, Hongzhou (John), Girod, Douglas, Thomas, Sufi Mary
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815928/
https://ncbi.nlm.nih.gov/pubmed/26540318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoto.2015.2381
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