Mapping epitopes of U1-70K autoantibodies at single-amino acid resolution

The mechanisms underlying development of ribonucleoprotein (RNP) autoantibodies are unclear. The U1-70K protein is the predominant target of RNP autoantibodies, and the RNA binding domain has been shown to be the immunodominant autoantigenic region of U1-70K, although the specific epitopes are not k...

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Publicado en:Autoimmunity
Autores principales: Haddon, David James, Jarrell, Justin Ansel, Diep, Vivian K., Wand, Hannah E., Price, Jordan V., Tangsombatvisit, Stephanie, Credo, Grace M., Mackey, Sally, Dekker, Cornelia L., Baechler, Emily C., Liu, Chih Long, Varma, Madoo, Utz, Paul J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815922/
https://ncbi.nlm.nih.gov/pubmed/26333287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916934.2015.1077233
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