Polymorphism in TGFB1 is associated with worse non-relapse mortality and overall survival after stem cell transplantation with unrelated donors

Transforming growth factor β-1, encoded by the TGFB1 gene, is a cytokine that plays a central role in many physiological and pathogenic processes. We have sequenced TGFB1 regulatory region and assigned allelic genotypes in a large cohort of hematopoietic stem cell transplantation patients and donors...

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Publicat a:Haematologica
Autors principals: Arrieta-Bolaños, Esteban, Mayor, Neema P., Marsh, Steven G.E., Madrigal, J. Alejandro, Apperley, Jane F., Kirkland, Keiren, Mackinnon, Stephen, Marks, David I., McQuaker, Grant, Perry, Julia, Potter, Michael N., Russell, Nigel H., Thomson, Kirsty, Shaw, Bronwen E.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815730/
https://ncbi.nlm.nih.gov/pubmed/26611472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.134999
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