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Using experimental evolution to probe molecular mechanisms of protein function

Directed evolution is a powerful tool for engineering protein function. The process of directed evolution involves iterative rounds of sequence diversification followed by assaying activity of variants and selection. The range of sequence variants and linked activities generated in the course of an...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Protein Sci
Main Authors: Fischer, Marlies, Kang, Mandeep, Brindle, Nicholas Pj
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815336/
https://ncbi.nlm.nih.gov/pubmed/26509591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2836
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