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Using experimental evolution to probe molecular mechanisms of protein function

Directed evolution is a powerful tool for engineering protein function. The process of directed evolution involves iterative rounds of sequence diversification followed by assaying activity of variants and selection. The range of sequence variants and linked activities generated in the course of an...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Fischer, Marlies, Kang, Mandeep, Brindle, Nicholas Pj
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815336/
https://ncbi.nlm.nih.gov/pubmed/26509591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2836
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