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Pro-inflammatory miR-223 mediates the cross-talk between the IL23 pathway and the intestinal barrier in inflammatory bowel disease

BACKGROUND: The IL23/Th17 pathway is essential for the onset of inflammatory bowel disease (IBD), yet the specific mechanism by which this pathway initiates the disease remains unknown. In this study, we identify the mechanisms that mediate cross-talk between the IL23 pathway and the intestinal barr...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Wang, Huiling, Chao, Kang, Ng, Siew Chien, Bai, Alfa Hc, Yu, Qiao, Yu, Jun, Li, Manying, Cui, Yi, Chen, Minhu, Hu, Ji-Fan, Zhang, Shenghong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815271/
https://ncbi.nlm.nih.gov/pubmed/27029486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0901-8
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