In situ detection of GM1 and GM2 gangliosides using immunohistochemical and immunofluorescent techniques for auxiliary diagnosis of canine and feline gangliosidoses

BACKGROUND: GM1 and GM2 gangliosidoses are progressive neurodegenerative lysosomal storage diseases resulting from the excessive accumulation of GM1 and GM2 gangliosides in the lysosomes, respectively. The diagnosis of gangliosidosis is carried out based on comprehensive findings using various types...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: Kohyama, Moeko, Yabuki, Akira, Ochiai, Kenji, Nakamoto, Yuya, Uchida, Kazuyuki, Hasegawa, Daisuke, Takahashi, Kimimasa, Kawaguchi, Hiroaki, Tsuboi, Masaya, Yamato, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815186/
https://ncbi.nlm.nih.gov/pubmed/27036194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-016-0691-y
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