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Sample size calculation while controlling false discovery rate for differential expression analysis with RNA-sequencing experiments

BACKGROUND: RNA-Sequencing (RNA-seq) experiments have been popularly applied to transcriptome studies in recent years. Such experiments are still relatively costly. As a result, RNA-seq experiments often employ a small number of replicates. Power analysis and sample size calculation are challenging...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Bi, Ran, Liu, Peng
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815167/
https://ncbi.nlm.nih.gov/pubmed/27029470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0994-9
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