A heat-inactivated H7N3 vaccine induces cross-reactive cellular immunity in HLA-A2.1 transgenic mice

BACKGROUND: Cross-reactive immunity against heterologous strains of influenza virus has the potential to provide partial protection in individuals that lack the proper neutralizing antibodies. In particular, the boosting of memory CD8+ T cell responses to conserved viral proteins can attenuate disea...

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Veröffentlicht in:Virol J
Hauptverfasser: Di Mario, Giuseppina, Garulli, Bruno, Sciaraffia, Ester, Facchini, Marzia, Donatelli, Isabella, Castrucci, Maria R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815128/
https://ncbi.nlm.nih.gov/pubmed/27036323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-016-0513-7
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