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Free light chains: potential biomarker and predictor of mortality in alpha-1-antitrypsin deficiency and usual COPD

BACKGROUND: Circulating free light chains (FLCs) can alter neutrophil migration, apoptosis and activation and may be a biomarker of autoimmune disease and adaptive immune system activation. These pathogenic roles could be relevant to lung disease in alpha 1 antitrypsin deficiency (A1ATD) and chronic...

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Publicado en:Respir Res
Main Authors: Hampson, Judith A., Stockley, Robert A., Turner, Alice M.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815123/
https://ncbi.nlm.nih.gov/pubmed/27036487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0348-1
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