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Imipramine alters the sterol profile in Leishmania amazonensis and increases its sensitivity to miconazole
BACKGROUND: Imipramine, a tricyclic antidepressant widely used clinically, has other pharmacological effects, such as antileishmanial activity. Tricyclic antidepressants interact with lipid bilayers, and some studies have shown that imipramine inhibits methyltransferases. Leishmania spp. produces co...
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| Publicado no: | Parasit Vectors |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4815111/ https://ncbi.nlm.nih.gov/pubmed/27036654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-016-1467-8 |
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