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Lipid-laden cells differentially distributed in the aging brain are functionally active and correspond to distinct phenotypes

We characterized cerebral Oil Red O-positive lipid-laden cells (LLC) of aging mice evaluating their distribution, morphology, density, functional activities and inflammatory phenotype. We identified LLC in meningeal, cortical and neurogenic brain regions. The density of cerebral LLC increased with a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shimabukuro, Marilia Kimie, Langhi, Larissa Gutman Paranhos, Cordeiro, Ingrid, Brito, José M., Batista, Claudia Maria de Castro, Mattson, Mark P., de Mello Coelho, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814830/
https://ncbi.nlm.nih.gov/pubmed/27029648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23795
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