The importance of G2677T/A and C3435T polymorphisms of the MDR1 gene in the aetiology of colorectal cancer

INTRODUCTION: Colorectal cancer (CRC) is the most common cancer among patients, and its aetiology is still not precisely known. It is believed that 15–30% of colorectal cancers are genetically determined. P-glycoprotein (P-gp) encoded by the MDR1 gene in normal conditions plays an important role in...

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Bibliographische Detailangaben
Veröffentlicht in:Prz Gastroenterol
Hauptverfasser: Stańko, Grzegorz, Kamiński, Marek, Bogacz, Anna, Seremak-Mrozikiewicz, Agnieszka, Kosiński, Bogusław, Bartkowiak-Wieczorek, Joanna, Kotrych, Daniel, Czerny, Bogusław
Format: Artigo
Sprache:Inglês
Veröffentlicht: Termedia Publishing House 2015
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814531/
https://ncbi.nlm.nih.gov/pubmed/27110309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/pg.2015.51185
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