Mycobacterium tuberculosis Zinc Metalloprotease-1 Elicits Tuberculosis-Specific Humoral Immune Response Independent of Mycobacterial Load in Pulmonary and Extra-Pulmonary Tuberculosis Patients

Conventionally, facultative intracellular pathogen, Mycobacterium tuberculosis, the tuberculosis (TB) causing bacilli in human is cleared by cell-mediated immunity (CMI) with CD4(+) T cells playing instrumental role in protective immunity, while antibody-mediated immunity (AMI) is considered non-pro...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Vemula, Mani H., Ganji, Rakesh, Sivangala, Ramya, Jakkala, Kiran, Gaddam, Sumanlatha, Penmetsa, Sitaramaraju, Banerjee, Sharmistha
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814508/
https://ncbi.nlm.nih.gov/pubmed/27065979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00418
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