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PER1 rs3027172 Genotype Interacts with Early Life Stress to Predict Problematic Alcohol Use, but Not Reward-Related Ventral Striatum Activity

Increasing evidence suggests that the circadian and stress regulatory systems contribute to alcohol use disorder (AUD) risk, which may partially arise through effects on reward-related neural function. The C allele of the PER1 rs3027172 single nucleotide polymorphism (SNP) reduces PER1 expression in...

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Detalhes bibliográficos
Publicado no:Front Psychol
Main Authors: Baranger, David A. A., Ifrah, Chloé, Prather, Aric A., Carey, Caitlin E., Corral-Frías, Nadia S., Drabant Conley, Emily, Hariri, Ahmad R., Bogdan, Ryan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814479/
https://ncbi.nlm.nih.gov/pubmed/27065929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyg.2016.00464
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