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Spatial regulation of cell cohesion by Wnt5a during second heart field progenitor deployment
Wnt5a, a non-canonical Wnt ligand critical for outflow tract (OFT) morphogenesis, is expressed specifically in second heart field (SHF) progenitors in the caudal splanchnic mesoderm (SpM) near the inflow tract (IFT). Using a conditional Wnt5a gain of function (GOF) allele and Islet1-Cre, we broadly...
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Publié dans: | Dev Biol |
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Auteurs principaux: | , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814329/ https://ncbi.nlm.nih.gov/pubmed/26916252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.02.017 |
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