Spatial regulation of cell cohesion by Wnt5a during second heart field progenitor deployment

Wnt5a, a non-canonical Wnt ligand critical for outflow tract (OFT) morphogenesis, is expressed specifically in second heart field (SHF) progenitors in the caudal splanchnic mesoderm (SpM) near the inflow tract (IFT). Using a conditional Wnt5a gain of function (GOF) allele and Islet1-Cre, we broadly...

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Gepubliceerd in:Dev Biol
Hoofdauteurs: Li, Ding, Sinha, Tanvi, Ajima, Rieko, Seo, Hwa-Seon, Yamaguchi, Terry, Wang, Jianbo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814329/
https://ncbi.nlm.nih.gov/pubmed/26916252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.02.017
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