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miR-8 modulates cytoskeletal regulators to influence cell survival and epithelial organization in Drosophila wings

The miR-200 microRNA family plays important tumor suppressive roles. The sole Drosophila miR-200 ortholog, miR-8 plays conserved roles in Wingless, Notch and Insulin signaling pathways linked to tumorigenesis, yet homozygous null animals are viable and often appear morphologically normal. We observe...

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Foilsithe in:Dev Biol
Main Authors: Bolin, Kelsey, Rachmaninoff, Nicholas, Moncada, Kea, Pula, Katharine, Kennell, Jennifer, Buttitta, Laura
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814314/
https://ncbi.nlm.nih.gov/pubmed/26902111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.01.041
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