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UHRF1 regulation of Dnmt1 is required for pre-gastrula zebrafish development
Landmark epigenetic events underlie early embryonic development, yet how epigenetic modifiers are regulated to achieve rapid epigenome re-patterning is not known. Uhrf1 and DNA methyltransferase 1 (Dnmt1) are known to largely mediate maintenance DNA methylation and Uhrf1 is also required for both Dn...
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| Published in: | Dev Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814311/ https://ncbi.nlm.nih.gov/pubmed/26851214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2016.01.036 |
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