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Somatic frameshift mutations in the Bloom syndrome BLM gene are frequent in sporadic gastric carcinomas with microsatellite mutator phenotype

BACKGROUND: Genomic instability has been reported at microsatellite tracts in few coding sequences. We have shown that the Bloom syndrome BLM gene may be a target of microsatelliteinstability (MSI) in a short poly-adenine repeat located in its coding region. To further characterize the involvement o...

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Wedi'i Gadw mewn:
Cyhoeddwyd yn:BMC Genet
Prif Awduron: Calin, George, Ranzani, Guglielmina N, Amadori, Dino, Herlea, Vlad, Matei, Irina, Barbanti-Brodano, Giuseppe, Negrini, Massimo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2001
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48142/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11532193/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2156-2-14
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