Four-Week Studies of Oral Hypoxia-Inducible Factor–Prolyl Hydroxylase Inhibitor GSK1278863 for Treatment of Anemia

Hypoxia-inducible factor prolyl hydroxylase inhibitors stabilize levels of hypoxia-inducible factor that upregulate transcription of multiple genes associated with the response to hypoxia, including production of erythropoietin. We conducted two phase 2a studies to explore the relationship between t...

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Опубликовано в: :J Am Soc Nephrol
Главные авторы: Holdstock, Louis, Meadowcroft, Amy M., Maier, Rayma, Johnson, Brendan M., Jones, Delyth, Rastogi, Anjay, Zeig, Steven, Lepore, John J., Cobitz, Alexander R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2016
Предметы:
Clinical Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814173/
https://ncbi.nlm.nih.gov/pubmed/26494831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014111139
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