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A thalamic input to the nucleus accumbens mediates opiate dependence

Chronic opiate use induces opiate dependence, which is characterized by extremely unpleasant physical and emotional feelings after drug use is terminated. Both rewarding effects of drug and the desire to avoid withdrawal symptoms motivate continued drug use(1-3), and the nucleus accumbens (NAc) is i...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Zhu, Yingjie, Wienecke, Carl F.R., Nachtrab, Gregory, Chen, Xiaoke
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814115/
https://ncbi.nlm.nih.gov/pubmed/26840481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16954
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